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- rabbit polyclonal IgG, 200 µg/ml
- epitope corresponding to amino acids 1-140 representing full length α-synuclein of human origin
- recommended for detection of α-synuclein, β-synuclein and γ-synuclein of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
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주문정보논문정보
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α/β/γ-synuclein Background Information
The synucleins, including å-synuclein (also designated NACP for nonamyloid component precursor), ∫-synuclein (also designated PNP 14 for phospho-neuroprotein 14) and ©-synuclein (also designated persyn or BCSG1 for breast cancer-specific gene 1) are presynaptic proteins abundant in neurons. Synucleins are predominantly expressed in the brain and are speculated to be involved in synaptic regulation and neuronal plasticity. å-Synuclein, identified as a component of Alzheimer’s disease amyloid plaques, is localized to neuronal cell bodies and synapses. Coordinate expression of å-synuclein and ∫-synuclein may be important during hematopoetic cell differentiation. A mutant form of å-synuclein is found in patients with early onset Parkinson’s disease. ©-Synuclein is associated with axonal pathology in Parkinson’s disease.
| α/β/γ-synuclein (FL-140) 논문정보 |
α/β/γ-synuclein (FL-140): sc-10717 antibody 및 α/β/γ-synuclein (FL-140) antibody conjugates를 사용한 논문들을 보세요.
7 total citations 논문 자료 로드 중입니다.
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α/β/γ-synuclein (FL-140)
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α/β/γ-synuclein (FL-140): sc-10717. Western blot analysis of α/β/γ-synuclein expression in mouse brain tissue extract.
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