santa cruz biotechnology, inc.
goat polyclonal IgG, 200 µg/ml epitope mapping at the C-terminus of PI 3-kinase p110α of human origin recommended for detection of PI 3-kinase p110α of mouse, rat and human origin by WB, IF and ELISA; also reactive with additional species, including equine, canine, bovine and avian blocking peptide, sc-1331 P
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Species
유전자 이름 (Gene Name)
유전자 ID
염색체 위치
Isoform (mRNA) Accession #
Protein Accession #
OMIM™ Number
Human
PIK3CA
5290
3q26.32
NM_006218
P42336
604370
Mouse
Pik3ca
18706
3 A3
P42337
없음
PI 3-kinase p110α Background Information Phosphatidylinositol 3-kinase (PI 3-kinase) is composed of p85 and p110 subunits. p85 lacks PI 3-kinase activity and acts as an adapter, coupling p110 to activated protein tyrosine kinase. Two forms of p85 have been described (p85å and p85∫), each possessing one SH3 and two SH2 domains. Various p110 isoforms have been identified. p110å and p110∫ interact with p85å, and p110å has also been shown to interact with p85∫ in vitro. p110∂ expression is restricted to white blood cells. It has been shown to bind p85å and ∫, but it apparently does not phosphorylate these subunits. p110∂ seems to have the capacity to autophosphorylate. p110© does not interact with the p85 subunits. It has been shown to be activated by å and ∫© heterotrimeric G proteins.
PI 3-kinase p110α (C-17) 논문정보
PI 3-kinase p110α (C-17): sc-1331 antibody 및 PI 3-kinase p110α (C-17) antibody conjugates를 사용한 논문들을 보세요.
13 total citations 논문 자료 로드 중입니다.
PI 3-kinase p110α (C-17)
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PI 3-kinase p110α (C-17): sc-1331. Immunoperoxidase staining of formalin fixed, paraffin-embedded human bronchus tissue showing cytoplasmic staining of respiratory epithelial cells.
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