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- goat polyclonal IgG, 200µg/ml
- epitope mapping near the N-terminus of GALE of human origin
- recommended for detection of GALE of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
- blocking peptide, sc-160058 P
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주문정보
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| Species |
유전자 이름 (Gene Name) |
유전자 ID |
염색체 위치 |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
GALE |
2582 |
1p36.11 |
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Q14376
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606953 |
| Mouse |
Gale |
74246 |
4 D3 |
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Q8R059
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없음 |
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GALE Background Information
GALE, also known as galactowaldenase, UDP-galactose-4-epimerase or SDR1E1, is a 348 amino acid protein that functions as the third enzyme in the Leloir pathway of galactose metabolism. A member of the sugar epimerase family, GALE exists as a homodimer, binds FAD as a cofactor and catalyzes the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine and UDP-glucose to UDP-galactose. The gene encoding GALE maps to human chromosome 1p36.11 and mutations in this gene lead to the development of complex disorder known as epimerase-deficiency galactosemia (EDG) or galactosemia type 3, which is characterized by mental retardation, liver damage, cataracts and deafness. |
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GALE (E-13)
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GALE (E-13): sc-160058. Western blot analysis of GALE expression in non-transfected: sc-117752 (A) and human GALE transfected: sc-116373 (B) 293T whole cell lysates. GALE (E-13): sc-160058. Western blot analysis of GALE expression in non-transfected: sc-117752 (A) and human GALE transfected: sc-110864 (B) 293T whole cell lysates. GALE (E-13): sc-160058. Western blot analysis of GALE expression in non-transfected: sc-117752 (A) and human GALE transfected: sc-170673 (B) 293T whole cell lysates. GALE (E-13): sc-160058. Western blot analysis of GALE expression in MIA PaCa-2 (A), COLO 320DM (B) and Caki-1 (C) whole cell lysates.
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다운로드
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