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- goat polyclonal IgG, 200 µg/ml
- epitope mapping near the C-terminus of NARFL of human origin
- recommended for detection of NARFL of mouse, rat and human origin by WB, IP, IF and ELISA; non cross-reactive with NARF; also reactive with additional species, including bovine
- blocking peptide, sc-160561 P
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주문정보
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| Species |
유전자 이름 (Gene Name) |
유전자 ID |
염색체 위치 |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
NARFL |
64428 |
16p13.3 |
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Q9H6Q4
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611118 |
| Mouse |
Narfl |
67563 |
17 A3.3 |
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Q7TMW6
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없음 |
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NARFL Background Information
Prenylation and methylation are two forms of protein modification, both of which are important for a variety of functions, including membrane attachment, protein-protein interactions and signaling events. NARFL (nuclear prelamin A recognition factor-like), also known as cytosolic Fe-S cluster assembly factor NARFL, HPRN, PRN (protein related to Narf), LET1L or IOP1 (iron-only hydrogenase-like protein 1), is a 476 amino acid protein belonging to the NARF family. Widely expressed, NARFL is required for extramitochondrial sulfur and iron protein maturation and may indirectly negatively regulate HIF-1å expression. Existing as three alternatively spliced isoforms, NARFL is encoded by a gene that maps to human chromosome 16p13.3 and murine chromosome 17 A3.3. |
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NARFL (L-14)
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NARFL (L-14): sc-160561. Western blot analysis of NARFL expression in HeLa (A), Hep G2 (B), K-562 (C) and A-10 (D) whole cell lysates.
NARFL (L-14): sc-160561. Western blot analysis of NARFL expression in 293T whole cell lysate.
NARFL (L-14): sc-160561. Immunofluorescence staining of formalin-fixed Hep G2 cells showing cytoplasmic localization.
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