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- goat polyclonal IgG, 200 µg/ml
- epitope mapping near the N-terminus of WBP2 of human origin
- recommended for detection of WBP2 of mouse, rat and human origin by WB, IP, IF and ELISA; non cross-reactive with WBP1 or WBP5; also reactive with additional species, including equine and canine
- blocking peptide, sc-160905 P
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주문정보
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WBP2 Background Information
WW domain-binding protein 2 (WBP2) is a 261 amino acid protein expressed in most tissues. The WW domain is composed of 38 to 40 semi-conserved amino acids and is shared by various groups of proteins, including structural, regulatory and signaling proteins. The domain mediates protein-protein interactions through the binding of polyproline ligands. WBP2 binds to the WW domain of Yes-associated protein (YAP), WW domain containing E3 ubiquitin protein ligase 1 (AIP5) and WW domain containing E3 ubiquitin protein ligase 2 (AIP2). The gene encoding WBP2 is located on human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes, some of which are involved in tumor suppression and in the pathogenesis of Li-Fraumeni syndrome, early onset breast cancer and a predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. |
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WBP2 (N-14)
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WBP2 (N-14): sc-160905. Western blot analysis of WBP2 expression in non-transfected 293: sc-110760 (A), human WBP2 transfected 293: sc-111002 (B), HeLa (C) and SK-MEL-24 (D) whole cell lysates and mouse brain tissue extract (E). WBP2 (N-14): sc-160905. Western blot analysis of WBP2 expression in SK-MEL-28 whole cell lysate.
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다운로드
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