santa cruz biotechnology, inc.
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- goat polyclonal IgG, 200 µg/ml
- epitope mapping within an internal region of IFN-α of human origin
- recommended for detection of IFN-α isoforms of human origin by WB, IP, IF and ELISA
- blocking peptide, sc-17645 P
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주문정보
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IFN-α Background Information
The genes encoding type I interferons (IFNs), which include 14 IFN-å genes, 1 IFN-∫ gene, 1 IFN-w (also known as IFN-å II1) gene, and a number of IFN-w pseudogenes, are clustered on human chromosome 9. Interferon-å and -∫ are cytokines that are widely known to induce potent antiviral activity. They exert a variety of other biological effects, including antitumor and immunomodulatory activities and are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. IFN-w is antigenically different from human IFN-å, IFN-∫ or IFN-©, but is a component of natural mixtures of IFN species produced by virus-induced leukocytes or Burkitt's lymphoma cells. The type I interferon receptor (IFN-åR) interacts with IFN-å, IFN-∫ and IFN-w, and seems to be a multisubunit receptor. |
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IFN-α (D-19)
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IFN-a (D-19): sc-17645. Western blot analysis of human recombinant IFN-α
IFN-α (D-19): sc-17645. Western blot analysis of purified human IFN-α 2a (A) and IFN-α 2b (B).
IFN-α (D-19): sc-17645. Western blot analysis of full length human recombinant IFN-α1.
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