epitope mapping within an internal region of WWOX of human origin
recommended for detection of WWOX of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and avian
WWOX Background Information WWOX (WW domain containing oxidoreductase) protein is a candidate tumor suppressor consisting of two WW domains that influence protein-protein interactions, and a short chain dehydrogenase (SDR) domain, that influences sex-steroid metabolism (1,2). Modulation of the WWOX gene influences esophageal squamous cell carcinogenesis and tumorigenicity of breast cancer cell lines MDA-MB-435 and T47D (1–3). The murine homolog WOX1 localizes in the mitochondria, and contains a mitochondrial targeting sequence mapping within the SDR domain (4). JNK1 can physically associate with WOX1 and sequester WOX1-dependent apoptosis (5).
WWOX (N-19) 논문정보
WWOX (N-19): sc-20528 antibody 및 WWOX (N-19) antibody conjugates를 사용한 논문들을 보세요.
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WWOX (N-19)
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WWOX (N-19): sc-20528. Western blot analysis of WWOX expression in mouse ovary tissue extract.
WWOX (N-19): sc-20528. Western blot analysis of WWOX expression in mouse ovary tissue extract.
