MAGE Background Information The melanoma-associated antigen (MAGE) family consists of a number of antigens recognized by cytotoxic T lymphocytes. The MAGE genes were initially isolated from different kinds of tumors, and based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. MAGE genes encode for tumor-rejection antigens and are expressed in tumors of different histologic types, but not in normal tissues, with the exception of testis and placenta. Although a large number of MAGE genes have now been identified and extensively studied in tumors of various origin, their function in normal cells remains unknown.
MAGE (I-17)
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MAGE (I-17): sc-31320. Western blot analysis of MAGE expression in non-transfected: sc-110760 (A) and human MAGE-A1 transfected: sc-112260 (B) 293 whole cell lysates.
MAGE (I-17): sc-31320. Western blot analysis of MAGE-A1 expression in non-transfected: sc-110760 (A) and human MAGE-A1 transfected: sc-112260 (B) 293 whole cell lysates.
