 |
- goat polyclonal IgG, 200µg/ml
- epitope mapping at the N-terminus of NAT-1 of mouse origin
- recommended for detection of NAT-1 of mouse, rat and human origin by WB, IP, IF and ELISA;
- blocking peptide, sc-47224 P
|
|
| |
주문정보
추천하는 보조제품:
원하시는 application에 클릭해 주세요.
NAT-1 Background Information
Arylamine N-acetyltransferases (NAT-1 and NAT-2) catalyze N- or O-acetylation of heterocyclic and arylamine substrates in the detoxification of a wide array of drugs. Certain alleles causing high levels of N-acetyltransferase activity have been associated with colon and urinary bladder cancers, as NATs also bioactivate several known carcinogens. Both NAT-1 and NAT-2 are cytoplasmic proteins and play an active role in the detoxification of many arylamine and hydrazine drugs. N-acetylation polymorphism is determined by the level of NAT activity in liver tissues, and has been linked to the action and toxicity of drugs that contain amines. Human NAT-1 is the functional homolog of rodent NAT-2, while human NAT-2 is the functional homolog of rodent NAT-1. |
|
|
NAT-1 (T-14)
클릭하시면 확대된 이미지를 보실 수 있습니다.
|
|
NAT-1 (T-14): sc-47224. Western blot analysis of NAT-1 expression in 293T whole cell lysate.
NAT-1 (T-14): sc-47224. Western blot analysis of NAT-1 expression in Hep G2 whole cell lysate.
|
|
다운로드
|
|
