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Oct-3/4 (C-10) Antibody (항체): sc-5279

 |  Datasheet (데이터 시트)
  • mouse monoclonal IgG2b; 200 µg/ml
  • raised against amino acids 1-134 of Oct-3/4 of human origin
  • recommended for detection of Oct-3/4 of mouse, rat and human origin by WB, IP, IF, IHC(P), ELISA and indirect FCM using PE-conjugated goat anti-mouse IgG: sc-3738; non cross-reactive with Oct-3/4 isoform B
  • agarose conjugate for IP studies, sc-5279 AC, 500 µg/0.25 ml agarose
  • TransCruz reagent for Gel Supershift and ChIP applications, sc-5279 X, 200 µg/0.1 ml
 
다른 Octamer-Binding Protein Antibodies (항체) ...
 
주문정보논문정보
추천하는 보조제품:
원하시는 application에 클릭해 주세요.
WB   IP   IF   IHC(P)   FCM   Gel Shift   ChIP   siRNA  
 
Species 유전자 이름 (Gene Name) 유전자 ID 염색체 위치 Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human POU5F1 5460 6p21.33 NM_002701, NM_203289 Q01860
164177
Mouse Pou5f1 18999 17 B1 P20263
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통화

 주문정보
제품명카탈로그 번호 단위가격수량관심상품에 더하기즐겨찾기
Oct-3/4 (C-10) sc-5279 200 µg/ml $279
Oct-3/4 (C-10) AC sc-5279 AC 500µg/ml, 25%ag $366
Oct-3/4 (C-10) X sc-5279 X 200 µg/0.1 ml $279
 siRNA Gene Silencers (자세한 정보를 보시려면 제품명 클릭)
제품명카탈로그 번호 단위가격수량관심상품에 더하기즐겨찾기
Oct-3/4 siRNA (h) sc-36123 10 µM $258
Oct-3/4 siRNA (m) sc-36124 10 µM $258
Oct-3/4 siRNA (h2) sc-43980 10 µM $258
Oct-3/4 (h)-PR sc-36123-PR 10 µM $23
Oct-3/4 (m)-PR sc-36124-PR 10 µM $23
Oct-3/4 (h)-PR sc-43980-PR 10 µM $23
 shRNA Plasmids (자세한 정보를 보시려면 제품명 클릭)
제품명카탈로그 번호 단위가격수량관심상품에 더하기즐겨찾기
Oct-3/4 shRNA Plasmid (h) sc-36123-SH 20 µg $520
Oct-3/4 shRNA Plasmid (m) sc-36124-SH 20 µg $520
Oct-3/4 shRNA Plasmid (h) sc-43980-SH 20 µg $520
 shRNA Lentiviral Particles (자세한 정보를 보시려면 제품명 클릭)
제품명카탈로그 번호 단위가격수량관심상품에 더하기즐겨찾기
Oct-3/4 shRNA (h) Lentiviral Particles sc-36123-V 200 µl $625
Oct-3/4 shRNA (m) Lentiviral Particles sc-36124-V 200 µl $625
Oct-3/4 shRNA (h) Lentiviral Particles sc-43980-V 200 µl $625
 WB Positive Control Cell Lysates (자세한 정보를 보시려면 제품명 클릭)
제품명카탈로그 번호 단위가격수량관심상품에 더하기즐겨찾기
F9 Cell Lysate sc-2245 500 µg/200 µl $104
mouse kidney extract sc-2255 500 µg/200 µl $104

Oct-3/4 Background Information
POU5F1 (POU domain, class 5, transcription factor 1), also known as octamer-binding transcription factor-3 (Oct-3, Otf-3), octamer-binding transcription factor-4 (Oct-4, Otf-4) and Oct-3/4, modulates embryonic stem (ES) cell populations by influencing lineage commitment. Oct-3/4 sustains stem-cell self-renewal and differentiation pathways. Transcription factors containing the POU homeodomain regulate tissue-specific gene expression in lymphoid and pituitary differentiation and in early mammalian development. Oct-3/4 is capable of inducing rapid proliferation and tumorigenic properties of ES cells through activation of the UTF1 gene. In humans, two Oct-3/4 isoforms contribute to influencing the undifferentiated phenotype of ES cells. Oct-3/4 pseudogenes localizing to human chromosomes 10 and 8 are reported to be transcribed in certain cancer cell lines and tissues.

Oct-3/4 (C-10) 논문정보
Oct-3/4 (C-10): sc-5279 antibody 및 Oct-3/4 (C-10) antibody conjugates를 사용한 논문들을 보세요.


110 total citations
논문 자료 로드 중입니다.
 
Oct-3/4 (C-10)
클릭하시면 확대된 이미지를 보실 수 있습니다.
Oct-3/4 (C-10): sc-5279. Indirect, intracellular FCM analysis of fixed and permeabilized F9 cells stained with Oct-3/4 (C-10), followed by PE-conjugated goat anti-mouse IgG: sc-3738. Black line histogram represents the isotype control, normal mouse IgG2b: sc-3879.
Oct-3/4 (C-10): sc-5279. Immunofluorescence staining of paraformaldehyde fixed multicell mouse embryo showing nuclear localization. Kindly provided by Dr. Kira Foygel, Stanford University.
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