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- rabbit polyclonal IgG, 200 µg/ml
- epitope corresponding to amino acids 58-207 mapping at the C-terminus of TIMP-1 (tissue inhibitor of metalloproteinase-1) of human origin
- recommended for detection of TIMP-1 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including bovine
- agarose conjugate for IP studies, sc-5538 AC, 500 µg/0.25 ml agarose
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주문정보논문정보
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| Species |
유전자 이름 (Gene Name) |
유전자 ID |
염색체 위치 |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
TIMP1 |
7076 |
Xp11.23 |
NM_003254 |
P01033
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305370 |
| Mouse |
Timp1 |
21857 |
X A1.3 |
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P12032
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없음 |
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TIMP-1 Background Information
TIMP-1, TIMP-2, TIMP-3 and TIMP-4 (tissue inhibitor of metalloproteinases 1, 2, 3 and 4) complex with metalloproteinases such as collagenases, gelatin-ases and stromelysins, resulting in irreversible inactivation of the metallopro-teinase. TIMP-1 has been found to be identical to EPA (erythroid-potentiation activity). Parathyroid hormone has been shown to be a regulator of TIMP-2 in osteoblastic cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus and remodeling of the extracellular matrix during the folding of epithelia and in the formation, branching and expansion of epithelial tubes. TIMP-4 is most highly expressed in heart, with low levels expressed in liver, brain, lung, thymus and spleen.
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TIMP-1 (H-150): sc-5538 antibody 및 TIMP-1 (H-150) antibody conjugates를 사용한 논문들을 보세요.
30 total citations 논문 자료 로드 중입니다.
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TIMP-1 (H-150)
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TIMP-1 (H-150): sc-5538. Western blot analysis of non-glycosylated human recombinant TIMP-1.
TIMP-1 (H-150): sc-5538. Western blot analysis of TIMP-1 expression in non-transfected: sc-117752 (A) and human TIMP-1 transfected: sc-110547 (B) 293T whole cell lysates and truncated human recombinant TIMP-1 fusion protein (C). |
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