CD7 Background Information CD7 is a type I transmembrane glycoprotein that is expressed on pluripotential hemapoietic cells, most human thymocytes and some peripheral blood T cells (1,2). CD7 is a marker for pluripotential stem cell leukemias and T cell acute lymphocytic leukemia (3). A role for CD7 in the activation of T cells with g/d receptors has been suggested (4,5). CD8 T cells from patients infected with HIV-1 displayed profound down-modulation of CD7 expression as compared with healthy subjects (6). CD7 is among the pan-T-cell antigens down-regulated in acute infectious mononucleosis. (7).
CD7 (B-F12)
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CD7 (B-F12): sc-65304. Indirect FCM analysis of human peripheral blood leukocytes stained with CD7 (B-F12), followed by PE-conjugated goat anti-mouse IgG: sc-3738. Black line histogram represents the isotype control, normal mouse IgG1: sc-3877.
CD7 (B-F12): sc-65304. Western blot analysis of CD7 expression in CCRF-CEM whole cell lysate.
