 |
- rabbit polyclonal IgG, 200µg/ml
- epitope corresponding to amino acids 1-190 mapping at the N-terminus of OAS3 of mouse origin
- recommended for detection of OAS3 of mouse origin by WB, IP, IF and ELISA
- TransCruz reagent for Gel Supershift and ChIP applications, sc-99101 X, 200 µg/0.1 ml
|
|
| |
주문정보
추천하는 보조제품:
원하시는 application에 클릭해 주세요.
OAS3 Background Information
The 2'- 5'- oligoadenylate synthetase (OAS) family is comprised of four members: OAS1, OAS2, OAS3 and OASL. These proteins are induced by interferons and function to convert ATP into 2'- 5'- linked oligomers of adenosine in the presence of double-stranded RNA and magnesium ions. Copper, iron and zinc ions strongly inhibit the OAS enzymatic activity, while manganese ions can replace magnesium ions as an activator. The OAS family plays a significant role in the inhibition of cellular protein synthesis, apoptosis and growth, and its members are important factors in viral infection resistance. OAS3, also referred to as p100, contains three adjacent OAS1-like domains and maps to the human chromosome 12q24.2. |
|
|
OAS3 (M-190)
클릭하시면 확대된 이미지를 보실 수 있습니다.
|
|
OAS3 (M-190): sc-99101. Western blot analysis of OAS3 expression in AMJ2-C8 whole cell lysate.Family ReviewExpected MW = 121 kDa, Unknown extra band(s) at ~160 kDa, Expected /= Observed MW = 121 vs 121
|
|
다운로드
|
|
